The Lightbed Photodynamic Therapy (PDT) Cancer Treatment Trial

Update 31 Jan 24:Recruitment for this Study has now been completed. Watch this space for updates.

Monitoring treatment effect of photo-dynamic therapy using a lightbed (Light-bed-PDT) in cancer patients by Circulating Tumour Cell (CTC) analysis

Background

Prevalence of cancer diagnosis is high and attributable to 30% of all deaths in Australia. There is a need for better treatment combined with reliable assessments of treatment effectiveness. This pilot intervention study aims to assess the treatment effectiveness and safety of Light-bed-PDT for patients with cancer using Circulating Tumour Cell (CTC) specimen analyses.

What is Photodynamic Therapy (PDT)

PDT consists of two steps, the oral administration of a chlorophyll-based algal-derived food-grade liquid photosensitiser (Step 1), followed by LED light therapy the next day (Step 2). The photosensitiser has been shown to concentrate in cancer cells, and is activated by light from Light Emitting Diodes (LED) inducing cancer cell death, while also stimulating the immune system.

Seeking Adults Diagnosed With Any Type Of Cancer seeking Adults Diagnosed With Any Type Of Cancer

What will I be asked to do?

There will be 5 visits to NIIM within 2 weeks.
The first and the last visit will involve a CTC blood test to check your eligibilty.
There will be a fee of $850 for the CTC test, which will be reimbursed, if you are eligible for the treatment.
The treatment session will include:

Photodynamic Therapy (PDT) with Light-bed Session:

Step 1: Wed: oral administration of photosensitiser taken 16-20 hours before LED light therapy.
Step 2: The treatment session will include 1x 90 min Hyperbaric Oxygen Therapy (HBOT)discounted out-of-pocket cost) followed by 1x 30min lightbed on the same day.
Step 3: Another CTC blood test will be scheduled a week later to check treatment effectiveness

Please note:

Participation is voluntary.
We are grateful to the granting body who has made the lightbed treatment available for free to the trial participants.
There are no costs involved for the CTC test, if you are eligible for the trial. Eligibility is checked for your safety.
All clinical trials have been approved by the NHMRC endorsed ethics committee. This includes any out-of-pocket-costs required for the trial to be conducted.
Any potential out-of-pocket costs have been discounted for trial participants.

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